Excess fructose may play a role in diabetes, obesity and other health conditions

PharmaLive.com (23 November 2010) - more and more people have become aware of the dangers of excessive fructose diets. A new review on fructose in an upcoming issue of the journal of the American Society of Nephrology (JASN) indicates just how dangerous this simple sugar can be.

Richard j. Johnson, MD and Takahiko Nakagawa, MD (Division of kidney disease and hypertension, University of Colorado) provide insight into concise recent experimental studies and clinical understanding how excessive fructose, present in added sugars could play a role in arterial hypertension, diabetes, obesity and chronic kidney disease (CKD).

Dietary fructose is present mainly in food sugars added, honey and fruits.américains ingest more frequently sucrose, fructose syrup high fructose (HFCS), a mixture of free and glucose, fructose generally in a proportion of 55 45-corn and a disaccharide containing 50% 50% of glucose and fructose bound together.With the introduction of HFCS in the 1970s, has been an increased intake of fructose and obesity rates have increased at the same time.

"The link between excessive intake of fructose and metabolic syndrome is becoming more établi.Toutefois, in this literature review, we conclude that it also increased evidence that fructose may play a role in hypertension and renal disease.""Science shows us some there are potentially negative impact of excessive amounts of sugar and corn syrup high-fructose on cardiovascular and kidney health" explains Mr. Johnson.Il continues that "excessive intake of fructose could be seen as an increasingly risky food and beverage additive.

Concerned that physicians may be overlooking this health problem when counsel patients IRC dieting low in protein, Mr. Johnson and Mr. Nakagawa recommends that low-protein diets include an attempt to restrict the added sugars containing fructose.

Mr. Johnson and Mr. Nakagawa listed as inventors on several requests for patents related to the lowering of uric for treatment or prevention of hypertension, diabetes and foie gras.

Editor's note: this article is not intended to provide medical advice, diagnosis or treatment.

Source of the story:

The story above is reproduced (with drafting adaptations by staff at PharmaLive.com) materials provided by American Nephrology Society, via EurekAlert!, a service of AAAS.

Reference of the review:

Richard j. Johnson, MD and Takahiko Nakagawa, MD.Effects of fructose kidney biology and diseases of the American Society of Nephrology, 29 November 2010 .Journal DOI: 10.1681/ASN.2010050506

Note: If no author is given, the source is cited for this.

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